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Enhancing Pneumonectomy Prognosis: Precautionary Measures

May, 05, 2024 | Lung Cancer

KEY TAKEAWAYS

  • The study aimed to assess post-pneumonectomy complications’ prognostic significance and identify associated risk factors for early occurrence.
  • The results revealed early postoperative complications adversely impact pneumonectomy prognosis, emphasizing the critical need for careful patient selection.

While pneumonectomy, the surgical removal of an entire lung, carries inherent risks of complications and death, it continues to be a crucial tool in the fight against lung cancer.

Güntuğ Batıhan and the team aimed to evaluate the prognostic significance of postoperative complications following pneumonectomy and identify related risk factors.

The study included patients who underwent pneumonectomy for non-small cell lung cancer (NSCLC) from January 2008 to May 2021. Using univariate and multivariate analyses, factors contributing to early postoperative complications and overall survival were assessed.

The results revealed that of the 136 patients enrolled, 33 (24.3%) experienced early postoperative complications, while 7 (5.1%) encountered late postoperative complications. Independent variables affecting early postoperative complications included the amount of cigarette smoking and the operation side. Multivariate analysis identified smoking amount and pericardial invasion as factors associated with postoperative hemorrhage, while advanced age was linked to postoperative pneumonia development.

The study concluded that early postoperative complications significantly impact prognosis following pneumonectomy. Hence, meticulous patient selection and preoperative risk assessment are imperative for reducing complication rates and enhancing patient outcomes.

No funding was received.

Source: https://pubmed.ncbi.nlm.nih.gov/38702724/

Batıhan G, Ceylan KC, Kaya ŞÖ., et al. (2024). “Risk factors and prognostic significance of early postoperative complications for patients who underwent pneumonectomy for lung cancer.” J Cardiothorac Surg. 2024 May 3;19(1):272. doi: 10.1186/s13019-024-02777-w. PMID: 38702724.

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