The study aimed to integrate MAC-NCs to improve pro-apoptotic effects on AGS gastric cancer cells. The synthesised MAC-NCs showed potential as a selective anti-gastric cancer agent, however, more in vivo studies are needed to confirm these findings. Gastric cancer is a significant health concern, and the search for effective treatments is ongoing. Myricetin, […]
Boron Neutron Capture Therapy for Spinal Tumors
The study aimed to evaluate the efficacy and safety of BNCT for metastatic spinal tumors. The findings suggested that BNCT could be a novel therapeutic option for managing metastatic spinal tumors. Metastatic spinal tumors pose a significant challenge in oncology, often requiring complex management strategies. While radiation therapy has advanced, improving the quality […]
Venetoclax and Hypomethylating Agents in Coexisting MM and AML
The study aimed to explore clinical features and promising treatment strategies for the rare coexistence of MM and AML. The results showed that DNMT3A clonal hematopoiesis drives the coexistence of multiple myeloma and AML. Multiple myeloma (MM) and acute myeloid leukemia (AML) are distinct hematologic malignancies arising from different cell lineages. Their coexistence […]
New Bioinformatics-Based Model for Cervical Cancer Diagnosis
The study aimed to identify cervical cancer susceptibility genes and construct a mitophagy-related diagnostic model. Researchers identified cervical cancer susceptibility genes and created a clinical model for early diagnosis and treatment. Zhang Zhang and the team aimed to use bioinformatics to systematically identify cervical cancer susceptibility genes and construct a validated mitophagy-related gene […]
HD-MT With/Without IT-MT and WBRT for Primary CNS Lymphoma
The study aimed to evaluate the efficacy and safety of HD-MT with or without IT-MT and WBRT for PCNSL. The results showed no significant difference in efficacy between HD-MT alone or with IT-MT plus radiotherapy, with manageable side effects. Primary central nervous system lymphoma (PCNSL) is a rare and aggressive type of lymphoma. […]
Spinal Chondrosarcoma Subtypes: Prognosis and Treatment Analysis
The study aimed to analyze differences in clinical, molecular, therapeutic, and prognostic factors among spinal chondrosarcoma subtypes. The results showed upregulated p53/MDM2 pathway in MCS and DCS, with radical resection crucial for spinal chondrosarcoma. Spinal chondrosarcoma is more invasive and has a worse prognosis than extremity chondrosarcoma. Prognosis and treatment vary among chondrosarcoma […]
MOST RECENT
Plasma ccfDNA & mtDNA as Biomarkers in Breast Cancer
The study aimed to evaluate ccfDNA, mtDNA, and CTCs as treatment response biomarkers and their link to EMT. The results showed plasma ccfDNA and mtDNA are potential biomarkers for monitoring chemotherapy response in breast cancer. Breast cancer is the most common cancer among women, highlighting the critical need for non-invasive blood-based biomarkers for […]
Predicting eTNBC Response With TNBC-DX Genomic Test
The study aimed to evaluate the TNBC-DX test’s ability to predict response to neoadjuvant taxane-carboplatin chemotherapy in eTNBC. The primary endpoints were to determine pCR, DDFS, and OS. Researchers found the TNBC-DX test predicts response to neoadjuvant taxane-carboplatin therapy and long-term survival in eTNBC. In this study, there was an urgent need for […]
Impact of High-Dose Vitamin D on mCRC With Chemo+Bev
The SOLARIS phase 3 trial investigated the effect of high-dose vitamin D3 on PFS in patients with mCRC. Researchers found that high-dose vitamin D3 showed no overall benefit for PFS but may help patients with mCRC. Higher 25-hydroxyvitamin D levels have been linked to improved colorectal cancer (CRC) survival. The SUNSHINE phase II […]
Efficacy of ESG401 Trop2 ADC in HER2-Negative mBC- BMs
The study aimed to investigate the efficacy of ESG401 in treating BMs in patients with HER2-negative mBC. Researchers noticed consistent responses in both brain and systemic lesions; further investigation is ongoing. The study focuses on addressing the significant unmet medical need for effective treatments targeting brain metastases (BMs) in HER2-negative metastatic breast cancer […]
Advertisement